Bio — Scientific Advisory Board member

Dr. Richard Deth

Dr. Richard Deth is a molecular neuropharmacologist and Professor of Pharmacology at Northeastern University in Boston. His research efforts are directed toward elucidating the molecular events causing neuropsychiatric disorders in which oxidative stress and impaired methylation are prominent features. These include autism, ADHD, schizophrenia and Alzheimer’s disease.

His laboratory was first to discover the novel signaling mechanism of D4 dopamine receptor-stimulated phospholipid methylation, which appears to be important for neuronal synchronization during attention.

A key aspect of his work is regulation of the folate and B12-dependent enzyme methionine synthase, which supplies methyl groups to the D4 receptor and is inhibited by oxidative stress. Dr. Deth is the author of the book: “Molecular Origins of Human Attention: The Dopamine-Folate Connection”.

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